2. Customers love the eclectic artwork, old coffee makers, and cool vibe at 22nd Street Coffee in Ybor City. They praise the reasonable prices and the fantastic job the staff does in creating top-notch coffee that surpasses even well-known chains like Starbucks, with great service to match. 6. Unique facts about 22nd Street Coffee include its location in historic Ybor City, known for the US cigar industry, and its inspiration from the coffee-drinking culture of Cuban, Spanish, and Italian immigrants in early 20th century Tampa. The company combines old-world craftsmanship with modern technology to create a perfect cup of coffee. 7. 22nd Street Coffee specializes in creating a unique and memorable coffee experience for customers, drawing inspiration from the rich history of coffee culture in Ybor City. The business's passion for coffee is evident in their commitment to sharing their knowledge and love of coffee with the local community, offering a combination of old-world quality and new technology in their signature 22nd Street brand.